The Route 66 Casino Hotel offers over 1, slot and video. Route 66 Casino · Map · Central Ave SW. The casino is located 10 minutes West of Albuquerque on Interstate 40 at Exit Enjoy the best of both worlds at Route 66 RV Resort with our casino amenities. Hours · Known For. Route 66 Casino Hotel and RV Resort is located less than 20 minutes west of downtown Albuquerque. The Route 66 Casino is an Indian gaming casino owned by the Pueblo of Laguna. More than slots, craps, roulette and blackjack. Located less than 20 minutes from Downtown Albuquerque, the room hotel is designed with a good night's rest in mind. Albuquerque, NM Directions · () Call Now · More Info. Located less than 20 minutes from Downtown Albuquerque, you won't have to worry about traffic lights or commuters, the drive is straight and stress free highway. Relax by the pool during the day and try your luck at the casino at night. Poker alley and bingo parlor. Free Wi-Fi. . Every room offers your choice of a king or two queen-size beds, a inch. Reenergize with in-room. The room Route 66 Casino Hotel is designed with a good night's rest in mind. The room hotel features an inviting ambiance of lively designs, modern furnishings, and a choice of a king or two queen-size beds. likes · 56 talking about this · were here. Other. Every room offers you a choice of a. Casino. International buffet, travel center, nightclub, 3-star hotel. Route 66 Casino Hotel, Albuquerque, New Mexico.