These casinos and gaming sites are owned by 14 New Mexico. A warm and friendly environment with slot machines at the Main Casino. With three live entertainment venues, you'll find something around every corner. #2 Best Value of 24 Mexico. New Mexico has 23 Indian casinos and 4 Indian gaming travel centers located across 10 counties. 1. Swirls of Cash. Sunday - Thursday: 8 AM - 2 AM | Friday & Saturday: Join the fun at Santa Ana Star Casino Hotel, the best casino in New Mexico! Located just north of Albuquerque, NM, we offer Gaming, Bowling, Golf, Dining. It's a warm, friendly environment with slot machines. #1 Best Value of 24 Mexico Casino Hotels ; 2. Colorful bingo cards and round bingo balls w/numbers. . Indulge. Excite. Win. Seadust Cancun Family Resort · 6, reviews. DISCOVER NORTHERN NEW MEXICO AT ITS BEST! The casino is open every day. The Pyramid Cancun · 4, reviews. Learn More. Upcoming Events. The Travel center includes a casino area with 45 slot machines. No Smoking Facility. Read More! Sky City's Main Casino and the Travel Center's Slot Area is open 24 hours daily. Experience Vegas at Albuquerque's Sandia Casino! Test your luck at our slots or play poker, roulette & more! High limit & VIP lounge available. Our New Mexico casino is open 24/7 daily. at Isleta Resort & Casino. Must be 21+. Open 24 hours, 7 days a week! What's happening. Saturdays in. Unwind. Sky City Casino is open 24 hours daily.