Our New Mexico casino is open 24/7 daily. No Smoking Facility. at Isleta Resort & Casino. Must be 21+. The Travel center includes a casino area with 45 slot machines. A warm and friendly environment with slot machines at the Main Casino. Excite. These casinos and gaming sites are owned by 14 New Mexico. Open 24 hours, 7 days a week! What's happening. #2 Best Value of 24 Mexico. New Mexico has 23 Indian casinos and 4 Indian gaming travel centers located across 10 counties. Indulge. Sky City Casino is open 24 hours daily. Upcoming Events. Read More! Sky City's Main Casino and the Travel Center's Slot Area is open 24 hours daily. Colorful bingo cards and round bingo balls w/numbers. With three live entertainment venues, you'll find something around every corner. It's a warm, friendly environment with slot machines. #1 Best Value of 24 Mexico Casino Hotels ; 2. Saturdays in. Experience Vegas at Albuquerque's Sandia Casino! Test your luck at our slots or play poker, roulette & more! High limit & VIP lounge available. The Pyramid Cancun · 4, reviews. Unwind. Seadust Cancun Family Resort · 6, reviews. 1. DISCOVER NORTHERN NEW MEXICO AT ITS BEST! The casino is open every day. . Sunday - Thursday: 8 AM - 2 AM | Friday & Saturday: Join the fun at Santa Ana Star Casino Hotel, the best casino in New Mexico! Located just north of Albuquerque, NM, we offer Gaming, Bowling, Golf, Dining. Win. Learn More. Swirls of Cash.